Protein Info for OKFHMN_04580 in Escherichia coli ECRC100

Name: efeU
Annotation: Ferrous iron permease EfeU

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 35 to 56 (22 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details amino acids 117 to 142 (26 residues), see Phobius details amino acids 148 to 171 (24 residues), see Phobius details amino acids 182 to 203 (22 residues), see Phobius details amino acids 220 to 233 (14 residues), see Phobius details amino acids 248 to 266 (19 residues), see Phobius details PF03239: FTR1" amino acids 1 to 275 (275 residues), 300.1 bits, see alignment E=8e-94 TIGR00145: FTR1 family protein" amino acids 1 to 273 (273 residues), 351.5 bits, see alignment E=2e-109

Best Hits

Swiss-Prot: 100% identical to EFEU_SHISS: Ferrous iron permease EfeU (efeU) from Shigella sonnei (strain Ss046)

KEGG orthology group: K07243, high-affinity iron transporter (inferred from 99% identity to ecg:E2348C_1067)

Predicted SEED Role

"Ferrous iron transport permease EfeU"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (276 amino acids)

>OKFHMN_04580 Ferrous iron permease EfeU (Escherichia coli ECRC100)
MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLLAAALCLGLGIFINETT
GEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLEQAVDSALQRGNHHGWALV
MMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLATAVVLGFLLYWGGIRLNLGAF
FKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFDMSAVLSTHSLFGTLMEGIFGYQ
EAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA