Protein Info for OKFHMN_02535 in Escherichia coli ECRC100

Name: yciT
Annotation: DNA-binding transcriptional regulator YciT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 PF08280: HTH_Mga" amino acids 3 to 42 (40 residues), 26.3 bits, see alignment 1.2e-09 PF08279: HTH_11" amino acids 4 to 44 (41 residues), 35.6 bits, see alignment 1.4e-12 PF08220: HTH_DeoR" amino acids 4 to 59 (56 residues), 57.6 bits, see alignment E=1.7e-19 PF00455: DeoRC" amino acids 69 to 227 (159 residues), 159.7 bits, see alignment E=1.2e-50

Best Hits

Swiss-Prot: 100% identical to YCIT_ECOLI: Uncharacterized HTH-type transcriptional regulator YciT (yciT) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b1284)

Predicted SEED Role

"Transcriptional regulatory protein YciT"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (249 amino acids)

>OKFHMN_02535 DNA-binding transcriptional regulator YciT (Escherichia coli ECRC100)
MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKLSYLRRAHGFAVSLDSD
DVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLARTLGEQKKNVTIITVSSY
IAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHFSKAFIGIDGWQPETGFTGRD
MMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVERFNRVITDSKIRASDLMHLEHS
KLTVHVVDI