Protein Info for OKFHMN_01255 in Escherichia coli ECRC101

Name: ydeO
Annotation: acid stress response transcriptional regulator YdeO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details transmembrane" amino acids 109 to 133 (25 residues), see Phobius details PF12833: HTH_18" amino acids 157 to 231 (75 residues), 58.3 bits, see alignment E=8e-20 PF00165: HTH_AraC" amino acids 199 to 229 (31 residues), 31.2 bits, see alignment 1.8e-11

Best Hits

Swiss-Prot: 100% identical to YDEO_ECO57: HTH-type transcriptional regulator YdeO (Z2209) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 98% identity to ecg:E2348C_1626)

Predicted SEED Role

"Putative formate dehydrogenase oxidoreductase protein" in subsystem Formate hydrogenase

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (253 amino acids)

>OKFHMN_01255 acid stress response transcriptional regulator YdeO (Escherichia coli ECRC101)
MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPYERHFKEIGFNENTIKK
YLQCTNIQTVTMPVPAKFLRASNVPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIFAT
CKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCLYISESLLKKKLKQEQTTFSQ
ILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYAFRKHFGNSPKRVSKEYRCQRHT
GMNTGNTMNALAI