Protein Info for OKFHMN_01105 in Escherichia coli ECRC100

Name: yneJ
Annotation: Uncharacterized HTH-type transcriptional regulator YneJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 transmembrane" amino acids 218 to 235 (18 residues), see Phobius details PF00126: HTH_1" amino acids 3 to 62 (60 residues), 63.6 bits, see alignment E=1.4e-21 PF03466: LysR_substrate" amino acids 85 to 282 (198 residues), 156.6 bits, see alignment E=5.8e-50

Best Hits

Swiss-Prot: 97% identical to YNEJ_ECOLI: Uncharacterized HTH-type transcriptional regulator YneJ (yneJ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ece:Z2177)

Predicted SEED Role

"LysR family transcriptional regulator YneJ" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (293 amino acids)

>OKFHMN_01105 Uncharacterized HTH-type transcriptional regulator YneJ (Escherichia coli ECRC100)
MDLTQLEMFNAVAEAGSITQAAAIVHRVPSNLTTRLRQLETELGVDLFIRENQRLRLSPA
GHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAVRIPATLAEFNRRYPKIQF
SLSTGPSGTMLEGVLEGKLNAAFIDGPINHTAIDGIPVYREELMIVTPQGHAPVIRASQV
NGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESYHGMLACVVAGAGIALIPRSMLE
SMPGHHQVEAWPLAEQWCWLTTWLVWRRGAKTRPLEAFIQLLDVPDSTKQGYQ