Protein Info for OKFHMN_00265 in Escherichia coli ECRC100

Name: gspH
Annotation: type II secretion system minor pseudopilin GspH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 184 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR01708: type II secretion system protein H" amino acids 3 to 174 (172 residues), 62.9 bits, see alignment E=1.5e-21

Best Hits

Swiss-Prot: 43% identical to GSPH_KLEPN: Type II secretion system protein H (pulH) from Klebsiella pneumoniae

KEGG orthology group: K02457, general secretion pathway protein H (inferred from 100% identity to ece:L7037)

Predicted SEED Role

"General secretion pathway protein H"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (184 amino acids)

>OKFHMN_00265 type II secretion system minor pseudopilin GspH (Escherichia coli ECRC100)
MSQRGFTILEMMLILLLMGITAGLVLMSFPDSAQNHLQQQRERLQAQLDYALDRSQQDGL
LMGIQVRFDGWKFKVLQRGTAESPPTLAEGGDIWQGYVWQTWQPRRAAMGGKLPDDVRLE
LQYLRGLQWMSEHDDGAEPDILLLPGGEVTPFRLLFRQVGEEAVVGLQVDENGLMTLFEG
EVSL