Protein Info for OHPLBJKB_03775 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Lipopolysaccharide export system permease protein LptF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 53 to 70 (18 residues), see Phobius details amino acids 90 to 113 (24 residues), see Phobius details amino acids 261 to 282 (22 residues), see Phobius details amino acids 289 to 309 (21 residues), see Phobius details amino acids 322 to 341 (20 residues), see Phobius details PF03739: LptF_LptG" amino acids 1 to 338 (338 residues), 256.4 bits, see alignment E=2e-80 TIGR04407: LPS export ABC transporter permease LptF" amino acids 1 to 341 (341 residues), 374.4 bits, see alignment E=2.1e-116

Best Hits

Swiss-Prot: 100% identical to LPTF_SHIFL: Lipopolysaccharide export system permease protein LptF (lptF) from Shigella flexneri

KEGG orthology group: K07091, lipopolysaccharide export system permease protein (inferred from 100% identity to eco:b4261)

MetaCyc: 100% identical to lipopolysaccharide transport system protein LptF (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-237 [EC: 7.5.2.5]

Predicted SEED Role

"FIG000988: Predicted permease"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (359 amino acids)

>OHPLBJKB_03775 Lipopolysaccharide export system permease protein LptF (Escherichia coli HS(pFamp)R (ATCC 700891))
MRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLS
LFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRH
QDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSV
VVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTD
QMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYL
LFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV