Protein Info for OHPLBJKB_02259 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Glutathione S-transferase GST-6.0

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 PF02798: GST_N" amino acids 2 to 72 (71 residues), 24 bits, see alignment E=6.1e-09 PF13417: GST_N_3" amino acids 17 to 76 (60 residues), 28.1 bits, see alignment E=3.1e-10 PF13409: GST_N_2" amino acids 17 to 72 (56 residues), 32.1 bits, see alignment E=2.2e-11

Best Hits

Swiss-Prot: 98% identical to YNCG_ECOLI: Uncharacterized GST-like protein YncG (yncG) from Escherichia coli (strain K12)

KEGG orthology group: K11208, GST-like protein (inferred from 98% identity to eco:b1454)

Predicted SEED Role

"Uncharacterized GST-like protein yncG" in subsystem Glutathione: Non-redox reactions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>OHPLBJKB_02259 Glutathione S-transferase GST-6.0 (Escherichia coli HS(pFamp)R (ATCC 700891))
MIKVYGVPGWGSTISELMLTLADIPYQFVDVSGFDHEGASRELLKTLNPLCQVPTLALEN
DEIMTETAAIAFMVLDRRPDLAPPVGRAERQQFQRLLVWLVANVYPTFTFADYPERWASD
APEQLKKNVIEYRKSLYIWLNSQLTAEPYAFGEQLTLVDCYLCTMRTWGPGHEWFQDNAQ
NISAIADAVCQLPKLQEVLKRNEII