Protein Info for OHPLBJKB_02186 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Aryl-phospho-beta-D-glucosidase BglA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 479 PF00232: Glyco_hydro_1" amino acids 4 to 476 (473 residues), 436.2 bits, see alignment E=5.9e-135

Best Hits

Swiss-Prot: 53% identical to ARBB_DICCH: 6-phospho-beta-glucosidase (arbB) from Dickeya chrysanthemi

KEGG orthology group: K01223, 6-phospho-beta-glucosidase [EC: 3.2.1.86] (inferred from 100% identity to ecx:EcHS_A1615)

Predicted SEED Role

"6-phospho-beta-glucosidase (EC 3.2.1.86)" in subsystem Beta-Glucoside Metabolism (EC 3.2.1.86)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.86

Use Curated BLAST to search for 3.2.1.86

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (479 amino acids)

>OHPLBJKB_02186 Aryl-phospho-beta-D-glucosidase BglA (Escherichia coli HS(pFamp)R (ATCC 700891))
MSGFKKGFLWGGAVAAHQLEGGWNEGGKGISIADVMTAVAHGVPREVTEGVIDGLNYPNH
EAIDFYHRYKTDIQLFAEMGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECLKQ
GMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIRFASTVFTRYKEKVKYWMTFNEINNQ
VNFSESLCPFTNSGILYSPEEDINEREQIMYQAVHYELVASALAVQTGKSINPEFNIGCM
IAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPEDN
AILARGCVDFIGFSYYMSFTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGLRY
SLNWLWDHFQLPLFIVENGFGAVDQRQADGTVNDHYRIDYFASHIREMKKAVVEDGVDLI
GYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRDLIANNGENI