Protein Info for OHPLBJKB_02183 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: 'PTS system N,N'-diacetylchitobiose-specific EIIC component' transl_table=11

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 transmembrane" amino acids 35 to 56 (22 residues), see Phobius details amino acids 80 to 102 (23 residues), see Phobius details amino acids 114 to 133 (20 residues), see Phobius details amino acids 145 to 167 (23 residues), see Phobius details amino acids 191 to 213 (23 residues), see Phobius details amino acids 233 to 254 (22 residues), see Phobius details amino acids 300 to 321 (22 residues), see Phobius details amino acids 334 to 388 (55 residues), see Phobius details amino acids 406 to 429 (24 residues), see Phobius details TIGR00410: PTS system, lactose/cellobiose family IIC component" amino acids 15 to 436 (422 residues), 333.9 bits, see alignment E=7.9e-104 PF02378: PTS_EIIC" amino acids 32 to 365 (334 residues), 155.1 bits, see alignment E=1.2e-49

Best Hits

KEGG orthology group: K02761, PTS system, cellobiose-specific IIC component (inferred from 99% identity to ecw:EcE24377A_1738)

Predicted SEED Role

"PTS system, cellobiose-specific IIC component (EC 2.7.1.69)" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (440 amino acids)

>OHPLBJKB_02183 'PTS system N,N'-diacetylchitobiose-specific EIIC component' transl_table=11 (Escherichia coli HS(pFamp)R (ATCC 700891))
MGLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDG
FIAGLLHLNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAISYEQDDLLCGLTA
IGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIFCRLARNPKITITMPAA
VPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVI
ILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDA
FANCGGSGMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVP
FIMVPIVNCAIGYFFVSMEIISPVAYAVPWTTPGPLIAFLGTGGNWLALLVGFLCLGVAT
MIYLPFVIAANKVNNMTTNG