Protein Info for OHPLBJKB_02181 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Mannosyl-D-glycerate transport/metabolism system repressor MngR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 239 PF00392: GntR" amino acids 4 to 65 (62 residues), 66.7 bits, see alignment E=1.8e-22 PF08220: HTH_DeoR" amino acids 30 to 66 (37 residues), 22.9 bits, see alignment 8.4e-09 PF07702: UTRA" amino acids 87 to 218 (132 residues), 107.7 bits, see alignment E=6.5e-35

Best Hits

Swiss-Prot: 36% identical to YIDP_ECOLI: Uncharacterized HTH-type transcriptional regulator YidP (yidP) from Escherichia coli (strain K12)

KEGG orthology group: K03482, GntR family transcriptional regulator, glv operon transcriptional regulator (inferred from 100% identity to ecx:EcHS_A1621)

Predicted SEED Role

"Transcriptional regulator, GntR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (239 amino acids)

>OHPLBJKB_02181 Mannosyl-D-glycerate transport/metabolism system repressor MngR (Escherichia coli HS(pFamp)R (ATCC 700891))
MIFQKIARLLKSEINGYSWHVGDLLPSEAELAVRYNVSRNTLRKALSLLEGEGIIHRKHG
SGTYIQKKNFVAHIDHMNSFSEIAHKSGKEAGSQIMKFEVQDASPTIATELNLVPGEQVY
YIKRLRFIEDNAAQLEETWMSVARFPDLTVSHMQKSKFSYIENECGIKIIGTYETFSPTF
PTPEIASILRISPRDPILKIQTQAVDSNSIPLDYSLLYSNIIEFQVKYFFRDKSRRTEC