Protein Info for OHPLBJKB_01993 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Osmotically-inducible putative lipoprotein OsmE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 112 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF04355: SmpA_OmlA" amino acids 33 to 96 (64 residues), 35.6 bits, see alignment E=3.3e-13

Best Hits

Swiss-Prot: 100% identical to OSME_ECO57: Osmotically-inducible putative lipoprotein OsmE (osmE) from Escherichia coli O157:H7

KEGG orthology group: K04064, osmotically inducible lipoprotein OsmE (inferred from 100% identity to eco:b1739)

Predicted SEED Role

"Osmotically inducible lipoprotein E precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (112 amino acids)

>OHPLBJKB_01993 Osmotically-inducible putative lipoprotein OsmE (Escherichia coli HS(pFamp)R (ATCC 700891))
MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMSRAQVAQIAGKPSSEVS
MIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCAEYDTDPQAAK