Protein Info for OHPLBJKB_01943 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: HTH-type transcriptional regulator NimR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 PF02311: AraC_binding" amino acids 21 to 146 (126 residues), 22.2 bits, see alignment E=1.5e-08 PF12833: HTH_18" amino acids 179 to 255 (77 residues), 67.6 bits, see alignment E=1.5e-22

Best Hits

Swiss-Prot: 99% identical to NIMR_ECOLI: HTH-type transcriptional regulator NimR (nimR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to eco:b1790)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (272 amino acids)

>OHPLBJKB_01943 HTH-type transcriptional regulator NimR (Escherichia coli HS(pFamp)R (ATCC 700891))
MHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLILALHGAITCTVENALWM
VPPQYAVWIPGGVKHSNQVTANAELCFLFIEPSAVTMPTTCCTLKISPLCRELILTLANR
TTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKIRTMVEMMAKGPVEWGSLGQWA
GFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQGLVKGDTVQKVAHTLGYDSTTAFI
TMFKKGLGQTPGRYIAGLTTVSPQSAKPDPRQ