Protein Info for OHPLBJKB_01730 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 816 signal peptide" amino acids 1 to 57 (57 residues), see Phobius details PF11924: IAT_beta" amino acids 153 to 428 (276 residues), 374.3 bits, see alignment E=6.6e-116 PF09134: Invasin_D3" amino acids 541 to 633 (93 residues), 59.8 bits, see alignment E=4.6e-20

Best Hits

Predicted SEED Role

"adherence and invasion outermembrane protein (Inv,enhances Peyer's patches colonization)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (816 amino acids)

>OHPLBJKB_01730 hypothetical protein (Escherichia coli HS(pFamp)R (ATCC 700891))
MLARSGKVSMATKKRSGEEINDRQILCGMGIKLRRLTAGICLITQLAFPMAAAAQGVVNA
ATQQPVPAQFAIANANTVPYTLGALESAQSVAERFGISVAELRKLNQFRTFARGFDNVRQ
GDELDVPAQVSENNLTPPPGNSSGNLEQQIASTSQQIGSLLAEDMNSEQAANMARGWASS
QASGAMTDWLSRFGTARITLGVDEDFSLKNSQFDFLHPWYETPDNLFFSQHTLHRTDERT
QINNGLGWRHFTPTWMSGINFFFDHDLSRYHSRAGIGAEYWRDYLKLSSNGYLRLTNWRS
APELDNDYEARPANGWDVRAEGWLPAWPHLGGKLVYEQYYGDEVALFDKDDRQSNPHAIT
AGLNYTPFPLMTFSAEQRQGKQGENDTRFAVDFTWQPGSAMQKQLDPNEVAARRSLAGSR
YELVDRNNNIVLEYRKKELVRLTLTDPVTGKSGEVKSLVSSLQTKYALKGYNVEATALEA
AGGKVVTTGKDILVTLPAYRFTSTPETDNTWPIEVTAEDVKGNFSNREQSMVVVQAPTLS
QKDSSVSLSTQTLNADSHSTATLTFIAHDAAGNPVVGLVLSTRHEGVQDITLSDWKDNGD
GSYTQVLTTGAMSGTLTLMPQLNGVDAAKAPAVVNIISVSSSRTHSSNKIDKDSYLSGNP
IEVTVELRDENDKPVKEQKQQLNTAVSIDNVKPGVTTDWKETADGVYKATYTAYTRGSGL
TTKLLMQNWNEDLHTAGFIIDANPQSAKIATLSASNNGVLANENAANTVSVNVADEGSNP
INDHTVTFAVLSGSATCFNNQNTAKTDVNGLATFDL