Protein Info for OHPLBJKB_01247 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Hydrogenase-4 component B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 223 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 37 to 62 (26 residues), see Phobius details amino acids 80 to 100 (21 residues), see Phobius details amino acids 111 to 129 (19 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details PF00662: Proton_antipo_N" amino acids 72 to 108 (37 residues), 26.9 bits, see alignment 3.8e-10 PF00361: Proton_antipo_M" amino acids 136 to 205 (70 residues), 29.5 bits, see alignment E=4.6e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (223 amino acids)

>OHPLBJKB_01247 Hydrogenase-4 component B (Escherichia coli HS(pFamp)R (ATCC 700891))
MDALQLLTWSLILYLFACLASLFLLGLDRLAIKLSGITSLVGGVIGIISGITQLHAGVTL
VAHFATPFDFADLTLRMDSLSAFMVLVISLLVVVCSLYSLTYMREYEGKGAAAMGFFMNL
FIASMVALLVMDNAFWFIVLFEMMSLSSWFLVIARQDKTSINAGMLYFFIAHAGSVLIMI
AFLLMGRESGSLDFASFARFHFLRGWRRRCFCWPFSVLARKPG