Protein Info for OHPLBJKB_01246 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Hydrogenase-4 component B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 50 to 73 (24 residues), see Phobius details amino acids 80 to 105 (26 residues), see Phobius details amino acids 122 to 143 (22 residues), see Phobius details amino acids 160 to 181 (22 residues), see Phobius details amino acids 202 to 229 (28 residues), see Phobius details amino acids 250 to 272 (23 residues), see Phobius details amino acids 309 to 328 (20 residues), see Phobius details amino acids 429 to 448 (20 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 1 to 202 (202 residues), 135.2 bits, see alignment E=1.4e-43

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>OHPLBJKB_01246 Hydrogenase-4 component B (Escherichia coli HS(pFamp)R (ATCC 700891))
MMPLHSWLPRAHPAAPSHASALMSGVMVKIGIFGILKVAMDLLAQTGLPLWWGILVMAIG
AISALLGVLYALAEQDIKRLLAWSTVENVGIILLAVGVAMVGLSLHDPLLTVVGLLGALF
HLLNHALFKGLLFLGAGAIISLLHTHDMEKMGALAKRMPWTAAACLIGCLAISALPPLNG
FISEWYTWQSLFSLSRVEAVALQLAGPIAMVMLAVTGGLAVMCFVKMYGITFCGAPRSTH
AEEAQEVPNTMIVAMLLLAALCVLIALSASWLAPKIMHIAHAFTDTPPVTVASGIALVPG
TFHTRVTPSLLLLLLLAMPLLPGLYWLWCRSRRAAFRRTGDAWACGYGWENAMAPSGNGV
MQPLRVVFSALFRLRQQLDPTLRLNKGLAHVTARAQSTEPFWDERVIRPIVSATQRLAKE
IQHLQSGDFRLYCLYVVAALVVLLIAIAV