Protein Info for OHPLBJKB_00967 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Electron transfer flavoprotein-ubiquinone oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 PF01494: FAD_binding_3" amino acids 4 to 186 (183 residues), 35.3 bits, see alignment E=4.6e-12 PF03486: HI0933_like" amino acids 6 to 47 (42 residues), 28.3 bits, see alignment 4.2e-10 PF00890: FAD_binding_2" amino acids 6 to 38 (33 residues), 30.5 bits, see alignment (E = 1.3e-10) PF07992: Pyr_redox_2" amino acids 6 to 160 (155 residues), 30.6 bits, see alignment E=1.3e-10 PF01134: GIDA" amino acids 6 to 156 (151 residues), 26.1 bits, see alignment E=2.5e-09 PF01266: DAO" amino acids 6 to 58 (53 residues), 41 bits, see alignment 9.9e-14 PF12831: FAD_oxidored" amino acids 6 to 151 (146 residues), 37.3 bits, see alignment E=1.2e-12 PF13450: NAD_binding_8" amino acids 9 to 40 (32 residues), 29.5 bits, see alignment (E = 4.1e-10) PF21162: ETFQO_UQ-bd" amino acids 176 to 273 (98 residues), 29.5 bits, see alignment E=5.2e-10

Best Hits

Swiss-Prot: 98% identical to YGCN_ECOLI: Probable electron transfer flavoprotein-quinone oxidoreductase YgcN (ygcN) from Escherichia coli (strain K12)

KEGG orthology group: K00313, electron transfer flavoprotein-quinone oxidoreductase [EC: 1.5.5.-] (inferred from 99% identity to eoj:ECO26_3837)

Predicted SEED Role

"Probable electron transfer flavoprotein-quinone oxidoreductase YgcN (EC 1.5.5.-)" (EC 1.5.5.-)

Isozymes

Compare fitness of predicted isozymes for: 1.5.5.-

Use Curated BLAST to search for 1.5.5.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>OHPLBJKB_00967 Electron transfer flavoprotein-ubiquinone oxidoreductase (Escherichia coli HS(pFamp)R (ATCC 700891))
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
FHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECI
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
EVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALR
SCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDILQRYQH
VPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSV
RCL