Protein Info for OHPLBJKB_00323 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: Phosphopentomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01676: Metalloenzyme
  • amino acids 3 to 388 (386 residues), 191.2 bits, E=2.4e-60
• PF01663: Phosphodiest
  • amino acids 264 to 344 (81 residues), 25.4 bits, E=1.1e-09

Best Hits

Swiss-Prot: 99% identical to YHFW_ECOLI: Uncharacterized protein YhfW (yhfW) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to eco:b3380)

Predicted SEED Role

"Phosphopentomutase like (EC 5.4.2.7)" (EC 5.4.2.7)

MetaCyc Pathways

• superpathway of purine deoxyribonucleosides degradation (7/7 steps found)
• purine ribonucleosides degradation (6/6 steps found)
• superpathway of pyrimidine deoxyribonucleosides degradation (6/6 steps found)
• 2-deoxy-α-D-ribose 1-phosphate degradation (3/3 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway
• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 5.4.2.7

Use Curated BLAST to search for 5.4.2.7

Protein Sequence (408 amino acids)

>OHPLBJKB_00323 Phosphopentomutase (Escherichia coli HS(pFamp)R (ATCC 700891))
MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQLPTLEKLGLINALGYA
PGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRMPFCDVIDRVEQALVSAGW
QVERRGDELQFLWVNQAVAIGDNLEADLGQVYNITANLSVISFDDAIKIGRIVREQVQVG
RVITFGGLLTDSQRILDAAESKEGRFIGINAPRSGAYDNGFQVVHMGYGVDEKVQVPQKL
YEAGVPTVLVGKVADIVNNPYGVSWQNLVDSQRIMDITLNEFNTHPTAFICTNIQETDLA
GHAEDVARYAERLQVVDRNLARLVEAMQPDDCLVVMADHGNDPTIGHSHHTREVVPVLVY
QQGMIATQLGVRTTLSDVGATVCEFFRAPPPQNGRSFLSSLRFAGDTL