Protein Info for OHPLBJKB_00230 in Escherichia coli HS(pFamp)R (ATCC 700891)

Annotation: putative MFS-type transporter YhhS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 transmembrane" amino acids 30 to 52 (23 residues), see Phobius details amino acids 58 to 76 (19 residues), see Phobius details amino acids 96 to 116 (21 residues), see Phobius details amino acids 120 to 151 (32 residues), see Phobius details amino acids 163 to 186 (24 residues), see Phobius details amino acids 191 to 210 (20 residues), see Phobius details amino acids 231 to 255 (25 residues), see Phobius details amino acids 263 to 282 (20 residues), see Phobius details amino acids 294 to 314 (21 residues), see Phobius details amino acids 320 to 341 (22 residues), see Phobius details amino acids 353 to 374 (22 residues), see Phobius details amino acids 380 to 399 (20 residues), see Phobius details PF07690: MFS_1" amino acids 36 to 363 (328 residues), 93.2 bits, see alignment E=8.1e-31 amino acids 265 to 411 (147 residues), 46.4 bits, see alignment E=1.4e-16

Best Hits

Swiss-Prot: 100% identical to YHHS_ECOLI: Uncharacterized MFS-type transporter YhhS (yhhS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to ecf:ECH74115_4793)

Predicted SEED Role

"Transporter, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (416 amino acids)

>OHPLBJKB_00230 putative MFS-type transporter YhhS (Escherichia coli HS(pFamp)R (ATCC 700891))
MKHCCKNVVILMPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVMG
FSAFWAGLVISLQYFATLLSRPHAGRYADSLGPKKIVVLGLCGCFLSGLGYLTAGLTASL
PVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPL
GVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALAL
ASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFS
VEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFM
DLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWRLKKRPPEHVPEAASSS