Protein Info for OH686_23895 in Pseudomonas sp. S08-1

Annotation: Multidrug resistance transporter, Bcr/CflA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 43 to 62 (20 residues), see Phobius details amino acids 74 to 92 (19 residues), see Phobius details amino acids 99 to 120 (22 residues), see Phobius details amino acids 131 to 151 (21 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details amino acids 214 to 237 (24 residues), see Phobius details amino acids 247 to 265 (19 residues), see Phobius details amino acids 277 to 299 (23 residues), see Phobius details amino acids 311 to 330 (20 residues), see Phobius details amino acids 338 to 361 (24 residues), see Phobius details amino acids 367 to 387 (21 residues), see Phobius details PF07690: MFS_1" amino acids 14 to 354 (341 residues), 110.4 bits, see alignment E=9.4e-36 PF00083: Sugar_tr" amino acids 46 to 184 (139 residues), 28.8 bits, see alignment E=5.9e-11

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 70% identity to pmy:Pmen_1103)

Predicted SEED Role

"Multidrug resistance transporter, Bcr/CflA family" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (400 amino acids)

>OH686_23895 Multidrug resistance transporter, Bcr/CflA family (Pseudomonas sp. S08-1)
MPKPTRILLLMLMTLTALGEISTQLLIPALAELEQGFAARPGTSLAALSIFVAAFGLGQL
IVGPLSDRLGRRPVLIAGLLVYLAATGWMLLAGDLAEFITARALQGLGACSALVLARAVV
RDVWKAEAGPALALTVIGMLTSIVLAPMFGGQLTLHWGWQAPVLAAFSVGSIALLAVLFL
YKESNAQLDPHAGRLLGLAGDYWDLLQGRSLRTFALTLAFTYGAMFAVIAGSSAAYIKLL
GLSAAEYGLTFGAIVSGLIAGALFTQKKILQLGPQRIVAIGVALVATGAALTVLVHALFG
LSVLGLSLPQVLVTIGGGMVLPASVAGAVIPNAHRAGLAAGFMGFAQMAGATLAGVLLGL
LQDGTSWPMVLLHGLFATAAFAAFHLLRRGSSVVPLSASR