Protein Info for OH686_22105 in Pseudomonas sp. S08-1

Annotation: Periplasmic serine (ClpP class)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 40 to 60 (21 residues), see Phobius details amino acids 172 to 188 (17 residues), see Phobius details TIGR00706: signal peptide peptidase SppA, 36K type" amino acids 75 to 280 (206 residues), 163.7 bits, see alignment E=2.3e-52 PF00574: CLP_protease" amino acids 77 to 163 (87 residues), 25.5 bits, see alignment E=1.1e-09 PF01343: Peptidase_S49" amino acids 141 to 282 (142 residues), 116 bits, see alignment E=1.6e-37

Best Hits

KEGG orthology group: K04773, protease IV [EC: 3.4.21.-] (inferred from 78% identity to pmk:MDS_1676)

Predicted SEED Role

"Periplasmic serine proteases (ClpP class)"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>OH686_22105 Periplasmic serine  (ClpP class) (Pseudomonas sp. S08-1)
MSDEWKASTTAGGDEKAWKLLEKTLQVGVVEQRRARRWGIFFKLLAFVYLFGALALFAPG
LKLDKAASSAEHHTALIEVRGMIMADEEASADNIVSSLRAAFEDKKTKGIVLRINSPGGS
PVQSGYIYDEIKRLRGEHPDTKVYAVISDLGASGAYYIASAADQIYADKASLVGSIGVTA
ATFGFVGVMEKVGVDRRVYTSGEHKAFLDPFQPPKAEETRFWQSVLETTHKQFIESVKKG
RGERLKVDQHPELFSGLIWSGEQALELGLVDALGSSSYVAREVIGAKDIVDFTREENPFD
RFTKKLGTSVAERLAMWMGFQGPTLR