Protein Info for OH686_22045 in Pseudomonas sp. S08-1

Annotation: DNA internalization-related competence protein ComEC/Rec2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 742 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 43 to 64 (22 residues), see Phobius details amino acids 225 to 251 (27 residues), see Phobius details amino acids 259 to 280 (22 residues), see Phobius details amino acids 304 to 324 (21 residues), see Phobius details amino acids 330 to 349 (20 residues), see Phobius details amino acids 361 to 381 (21 residues), see Phobius details amino acids 390 to 411 (22 residues), see Phobius details amino acids 418 to 442 (25 residues), see Phobius details amino acids 450 to 482 (33 residues), see Phobius details PF13567: DUF4131" amino acids 21 to 168 (148 residues), 113.1 bits, see alignment E=1.7e-36 TIGR00361: DNA internalization-related competence protein ComEC/Rec2" amino acids 112 to 717 (606 residues), 318.3 bits, see alignment E=8.7e-99 PF03772: Competence" amino acids 201 to 464 (264 residues), 190.9 bits, see alignment E=4.5e-60 TIGR00360: ComEC/Rec2-related protein" amino acids 222 to 400 (179 residues), 80.5 bits, see alignment E=1.8e-26 PF00753: Lactamase_B" amino acids 501 to 687 (187 residues), 62.3 bits, see alignment E=9.4e-21

Best Hits

KEGG orthology group: K02238, competence protein ComEC (inferred from 66% identity to pfl:PFL_1775)

Predicted SEED Role

"DNA internalization-related competence protein ComEC/Rec2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (742 amino acids)

>OH686_22045 DNA internalization-related competence protein ComEC/Rec2 (Pseudomonas sp. S08-1)
MRTGMLALAAGLACLPLLPELPPTWLLLLALLPLALMLLPWRSYAISFLLFGFVWACCSA
QAALDDRLLPELDGRTLWLEGRVSGLPEVSEGVVRFQLEEPMARAHRLPEHLRLSWYDGP
KVLAGERWRLAVKLKRPRGLVNPQGFDYEAWLLAQRIGATGTIKQGERLSEATGPAAWRD
QLRQRLLGVEAHGRAGGLAALVLGDDSGLSRADWRTLQDTGTVHLLVISGQHVALLAAVL
YGLVAGLARLGLWPRLLPWLPWACGLAFAGALGYGVLAGFEVPVRRACVMVALVLLWRLR
FRHLGLWWPLALALILVLLVEPLASLQAGFWLSFGAVAVLVWVFGGRLGTWSWWRVWWRA
QWTLALGLLPLFFALGLPLSLSGPLANLVAVPWVSLLVVPLALLGTLLLPVPWLGEGLLW
LAGGLLELLFQLLAWIAALLPAWLPTALPLWCWLIGSLGVLLCLMPSGVPLRALGLAMLL
AFAVPPRERIPSGQAEIWQLDVGQGLAVLVRTREHALLYDAGPRFGDFDLGERVVLPSLR
QLDVSHLDLMLLSHADSDHAGGAEALARGLPIDRVLSGESAVLPASLAAQPCIDGASWSW
DGVRFTTWRWAGAGEGNPASCLLKVEAAGERLLLTGDIDEAAEAALLAAGRDLRAEWLQI
PHHGSRSSSSAAFLDAVAPRAALLSRGWHNPFGHPHPTVLARYRERDITLYDSAERGAVR
LLLGSGEGVSSWRERPRFWREK