Protein Info for OH686_20630 in Pseudomonas sp. S08-1

Annotation: Type I secretion outer membrane protein, TolC family or Type I secretion system, outer membrane component LapE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 21 to 430 (410 residues), 307.4 bits, see alignment E=8.6e-96 PF02321: OEP" amino acids 25 to 217 (193 residues), 76.2 bits, see alignment E=1.5e-25 amino acids 241 to 419 (179 residues), 75.6 bits, see alignment E=2.3e-25

Best Hits

KEGG orthology group: K12340, outer membrane channel protein TolC (inferred from 86% identity to pmy:Pmen_1804)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (451 amino acids)

>OH686_20630 Type I secretion outer membrane protein, TolC family or Type I secretion system, outer membrane component LapE (Pseudomonas sp. S08-1)
MPSLKPLYSGILLAMACLQAQAMTLSEAIQSTIDNHPELHASMNDRLSADEEVKIAKGGY
LPTVDLLLGYGREQTDSPSTRALGDHNKETLTYNDAELRLRQMLFDGFNTPNEVARTKSV
VDSRAYYVQGTSESLALRTVEVYLEVLKRREMVNLAQNNLQAHQRINDQIGLRSERGVGS
TADLDQSVARLALAENNLYTEQVNLADAEANFFSATGRMPDELEQPASIKGEMPEDVNVA
RQMVMDNNPFLKSAQADVNAAEKQYEVAKAPFYPRFDLELATTADDNVQGDEGHYNTWRA
AVVMNYNLFNGMRDKARLQSAAHQINQSMDIRNNALRVVNENLSLAWNAMENARLQTPKA
RDYADYTSRVREAYQQQFSLGQRTLLDLLDSDNELFTANRRYTEVRYTEEFSMYRVIAAM
GELLKKQNVVVPAEAVALTEVKSEARLPEMK