Protein Info for OH686_18820 in Pseudomonas sp. S08-1

Annotation: Transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 92 to 113 (22 residues), see Phobius details PF00126: HTH_1" amino acids 5 to 64 (60 residues), 64.8 bits, see alignment E=8.1e-22 PF03466: LysR_substrate" amino acids 91 to 292 (202 residues), 202.8 bits, see alignment E=6.5e-64 PF12727: PBP_like" amino acids 159 to 289 (131 residues), 33.3 bits, see alignment E=4.1e-12

Best Hits

Swiss-Prot: 46% identical to YEIE_ECOL6: Uncharacterized HTH-type transcriptional regulator YeiE (yeiE) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 88% identity to pmy:Pmen_1292)

Predicted SEED Role

"LysR family transcriptional regulator PA3398" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>OH686_18820 Transcriptional regulator, LysR family (Pseudomonas sp. S08-1)
MRFTLRQLEVFVAVAKQESVSRAAESLALSQSAASTSLSELERQSDCQLFDRAGKRLSLN
ALGRQLLPQAVALLDQAKEIERLLSGKTGFGLLELGATLTVGNYLATLLIGNFMQRHPEC
RLKLHVQNTANVVQRVAHYELDLGLIEGDCQHPDIEVQPWVEDELVVFCAPRHPLAERGT
ATLEELSREAWILREQGSGTRLTFDQAMRHHPAQLNIRLELEHTEAIKRAVESGLGIGCI
SRLALRDAFRRGSLVPVETPELDLTRQFYFIWHRQKYQTAAMREFLELCREMTAGIRRSD
EIVLQPIA