Protein Info for OH686_16845 in Pseudomonas sp. S08-1

Annotation: Kup system potassium uptake protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 59 to 79 (21 residues), see Phobius details amino acids 109 to 126 (18 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 177 to 200 (24 residues), see Phobius details amino acids 212 to 237 (26 residues), see Phobius details amino acids 256 to 276 (21 residues), see Phobius details amino acids 296 to 321 (26 residues), see Phobius details amino acids 348 to 369 (22 residues), see Phobius details amino acids 375 to 400 (26 residues), see Phobius details amino acids 406 to 425 (20 residues), see Phobius details amino acids 431 to 451 (21 residues), see Phobius details PF02705: K_trans" amino acids 22 to 473 (452 residues), 610.1 bits, see alignment E=2e-187 PF22776: K_trans_C" amino acids 485 to 633 (149 residues), 181.4 bits, see alignment E=1e-57

Best Hits

Swiss-Prot: 77% identical to KUP_PSEF5: Probable potassium transport system protein kup (kup) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 80% identity to avn:Avin_24540)

MetaCyc: 50% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (633 amino acids)

>OH686_16845 Kup system potassium uptake protein (Pseudomonas sp. S08-1)
MSSHIADAAGQSPSRSSSFGLLVAAIGVVYGDIGTSPLYTLKEVFAGHYGVRVDHDGVLG
ILSLILWSLLWVVSLKYVLFMLRADNGGEGGVMALTALARRATAAHPRLSGVLVLLGLFG
TALFYGDSMITPAISVLSAVEGLDVALPGMSHWVVPVTVILLIGLFLIQKHGTARIGILF
GPVMVLWFLVLGVLGIHGIVQRPEVLQALNPWWAVNFFVAHPGIGVTILGAVVLALTGAE
ALYADMGHFGRLPIARAWFALVLPGLVLNYFGQGALLLENPEAARNPFYLLAPSWALLPM
IGLATLATIIASQAVISGAFSLSQQAMQLGYIPRMQVQHTSSAAQGQIYVGVVNWALMVA
VVLLVIGFGSSGALAAAYGVAVTTTMLIDTLLVSAVMLLLWRTPRWLAIPVLLGFLLVDS
LFFSANVPKVLQGGAFPVVAGIALFLLMTTWKRGKQMLFARLDETALPLPAFLGSIRIQP
PHRVNGTAIFLSARPDAVPHALLHNLLHNQVLHEQVVLLTVVSEDEPRLAPERRFEVSAY
GDGFFRVILHFGFMEEPDVPAALRLCHLDELDFSPMRTTYFLSRETVIPTKRFGMAPWRE
RLFAFLQKNANSSMSYFQLPVNRVIELGTQVEI