Protein Info for OH686_14305 in Pseudomonas sp. S08-1

Annotation: GMP/IMP nucleotidase YrfG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 PF00702: Hydrolase" amino acids 9 to 176 (168 residues), 63.1 bits, see alignment E=7.1e-21 PF13419: HAD_2" amino acids 12 to 187 (176 residues), 38.7 bits, see alignment E=1.8e-13 PF12710: HAD" amino acids 12 to 141 (130 residues), 34.2 bits, see alignment E=5.3e-12 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 91 to 186 (96 residues), 41.4 bits, see alignment E=8.4e-15

Best Hits

KEGG orthology group: K07025, putative hydrolase of the HAD superfamily (inferred from 82% identity to pmy:Pmen_0392)

Predicted SEED Role

"FIG001957: putative hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (224 amino acids)

>OH686_14305 GMP/IMP nucleotidase YrfG (Pseudomonas sp. S08-1)
MHQLPWADIDTVLLDMDGTLLDLHFDNHFWLEHLPLRYAELHGISREAASAELLPLFRAH
AGTLPWYCTDFWSRELNLSVRDLKREVADLIALRPDADTFLAALRAAGKRVVLITNAHRD
SLSLKLEKVELAPYFDRLISSHDYGFPKEDQQFWFALQQDFPFEPARSLFIDDSLPILRS
AGRYGVAHLLAVRQPDSRGAAKDTEEFVAVEDYLQLSAQLAPPA