Protein Info for OH686_12080 in Pseudomonas sp. S08-1

Annotation: exodeoxyribonuclease V, gamma subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1086 TIGR01450: exodeoxyribonuclease V, gamma subunit" amino acids 2 to 1035 (1034 residues), 938.7 bits, see alignment E=2.4e-286 PF04257: Exonuc_V_gamma" amino acids 2 to 312 (311 residues), 331.7 bits, see alignment E=4.6e-103 PF17946: RecC_C" amino acids 789 to 1009 (221 residues), 163.9 bits, see alignment E=4.4e-52

Best Hits

KEGG orthology group: K03583, exodeoxyribonuclease V gamma subunit [EC: 3.1.11.5] (inferred from 74% identity to psa:PST_4034)

Predicted SEED Role

"Exodeoxyribonuclease V gamma chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1086 amino acids)

>OH686_12080 exodeoxyribonuclease V, gamma subunit (Pseudomonas sp. S08-1)
MLSLYHAPDLETLGLLACRLLAQPQADVLAPARVVVPSQGIGRWLTLQLAREQGIAMHLE
VQLPSSFVWGLARQVLGALPEQSAFNPQAMTWRLYDWLCEPTNLARAERLQRYLEGGDER
RRLALAAKIADVFDQYLLYRDDWLAAWERGELCDLGADESWQALLWQELTRDGHPHRARL
LGELLARLHAATPIDGMPERLLVFGISSLPPHHLRVLEGLARHTDVVIFALNPCREAWGE
IRDVRELAQSEVSPDDWYLDVGHPLLASLGKQGRDFFDSLLGQIAEENGIYPQDAELTDD
SLLHALQQDILRLRTRTPDERLALRDDDRSLELHIAHSPLREVEILHDQLLARFAADPRL
SPDQVVVLTPDIERYAPYIEAVFARREGAPHIPFSLADRSLRAETPLIEAFLGLLSLPES
RFAAEEILAWLEQPAIARRAGIEPEDLPLLRDWLHQAGVRWGRDAGHRAALDLPADDAFT
WRQGLDRLLLGFAAPPQLAGDGVPLLGDSLPLDALEGARGQLLGRLCAFVELLAGLAERL
QRDRPLADWALDLQGLIDVLFDERESGDTLLLLSQACAALGRQALDAGIERPLQLALVRQ
QLGAALESGSGASGFLTGAVTFCTMVPMRSLPFRLVCLLGLDDGALPRRTPVAGFDLIAR
RPRRGDRARRLDDRYLFLETLLSARDGLYLSYVGRDPRDNAELPPSVLVSELLETVDLTA
TRGESKASARITIDHPLQPFAPGNFAAASARQGFAPAWFRAARRLAEAPLLTPPAFIERL
PEPGEDWLTIEPSQLLQCFRHPARFLLEQRLGLRLADADEAIAADEPFALEGPARRGLRQ
LALQAVERGWSEEQERRIARAAGWLPPGELGHALWGKQRGPVRAFAPRLFEARPEETPQP
LLVDIELAGVRVHGWLDGVTSHGLFDWRLAAPGAWDLPGFWLRHLLLNVSATTGIARESL
LVSPAGDWQLGPLDNPEALLEPWLVAYRKALSAPLPFITRSSYEFAKALCTPSAKSRKEP
RDAARDKAEAAWLGAEFSPVPGEALDPWYALAFRERDPLGERFEQLAERLLGPALKALAS
GEEEAE