Protein Info for OH686_11680 in Pseudomonas sp. S08-1

Annotation: sulfate ABC transporter, permease protein CysW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 24 to 46 (23 residues), see Phobius details amino acids 67 to 94 (28 residues), see Phobius details amino acids 106 to 131 (26 residues), see Phobius details amino acids 146 to 166 (21 residues), see Phobius details amino acids 206 to 231 (26 residues), see Phobius details amino acids 252 to 272 (21 residues), see Phobius details TIGR02140: sulfate ABC transporter, permease protein CysW" amino acids 23 to 279 (257 residues), 396.5 bits, see alignment E=5.5e-123 TIGR00969: sulfate ABC transporter, permease protein" amino acids 28 to 278 (251 residues), 318.2 bits, see alignment E=4.6e-99 PF00528: BPD_transp_1" amino acids 85 to 281 (197 residues), 52.7 bits, see alignment E=2.4e-18

Best Hits

Swiss-Prot: 51% identical to CYSW_ECOL6: Sulfate transport system permease protein CysW (cysW) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02047, sulfate transport system permease protein (inferred from 88% identity to avn:Avin_31740)

MetaCyc: 51% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysW (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysW" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>OH686_11680 sulfate ABC transporter, permease protein CysW (Pseudomonas sp. S08-1)
MTTTTLSASAAANAARRGSAAGRIALIVGAWLAFAIFLLLPLLVVLHEALKLGLGTFFTA
LIEPDAISALNLTLLAVGISVPLNLVFGVAAAWCVSKYEFTGKSILVTLIDLPFSVSPVI
AGLIYVLLFGAQGFFGEWLQERDIQIIFALPGIVLATVFVTVPFVARELIPLMQEQGTQE
EEAARLLGANGWQMFWHVTLPNIKWGLIYGVVLCAARAMGEFGAVSVVSGHIRGYTNTLP
LHVEILYNEYNHVAAFSVASLLLALALIILLLKQWSEARLSRLKSNADEE