Protein Info for OH686_09540 in Pseudomonas sp. S08-1

Annotation: phosphatidylserine decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 196 to 217 (22 residues), see Phobius details TIGR00163: phosphatidylserine decarboxylase" amino acids 49 to 283 (235 residues), 256.5 bits, see alignment E=9.3e-81 PF02666: PS_Dcarbxylase" amino acids 63 to 282 (220 residues), 213.8 bits, see alignment E=9.8e-68

Best Hits

Swiss-Prot: 88% identical to PSD_PSEMY: Phosphatidylserine decarboxylase proenzyme (psd) from Pseudomonas mendocina (strain ymp)

KEGG orthology group: K01613, phosphatidylserine decarboxylase [EC: 4.1.1.65] (inferred from 86% identity to pfv:Psefu_4120)

Predicted SEED Role

"Phosphatidylserine decarboxylase (EC 4.1.1.65)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 4.1.1.65)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.65

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (286 amino acids)

>OH686_09540 phosphatidylserine decarboxylase (Pseudomonas sp. S08-1)
MKERLFILSQYLLPHHLLSRLIGFAAECRAAWFKDRLIGWFAKQYQVNMAEAQVQELTAY
EHFNAFFTRALKDGARPLDETPGAILCPADGAVSQLGPIEQGRCFQAKGHSFSVQELLGG
DAERAAPFMGGDFATVYLSPKDYHRVHMPLAGTLKEMVYVPGRLFSVNQTTAENVPELFA
RNERVVCLFDTERGPMAVVLVGAMIVASVETVWAGLVTPPKRELKTTHYDEASRAAIELS
KGGELGRFKLGSTAIVLFGPQQVQWAEGVVAGSPVRMGQALGLPRS