Protein Info for OH686_07455 in Pseudomonas sp. S08-1

Annotation: Response regulator c-di-GMP phosphodiesterase, RpfG family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 PF00072: Response_reg" amino acids 13 to 124 (112 residues), 91.7 bits, see alignment E=5.4e-30 PF13487: HD_5" amino acids 166 to 347 (182 residues), 103.5 bits, see alignment E=1.7e-33 PF01966: HD" amino acids 196 to 309 (114 residues), 29 bits, see alignment E=1.8e-10

Best Hits

Swiss-Prot: 58% identical to CDPD2_PSEAE: Cyclic di-GMP phosphodiesterase PA4781 (PA4781) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K07814, putative two-component system response regulator (inferred from 70% identity to pmy:Pmen_0836)

Predicted SEED Role

"Pole remodelling regulatory diguanylate cyclase" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (394 amino acids)

>OH686_07455 Response regulator c-di-GMP phosphodiesterase, RpfG family (Pseudomonas sp. S08-1)
MVDMLDRPDRPLVLLVDDTPENLELMSELLADSYRIKVANNGLKALRIAAGSQQPDLILL
DIMMPEMDGYEVCRLLKMNPATADIPVVFLTAKTEVADEQQGFDLGAVDYITKPISPPIV
LARVHAQLQLKASADFLRDKSEYLELEVRRRTRDMQRLQEVTIEAMASLAAMRDNPNGKH
LSRVEPYMVALAKALAYQQPALAAELSAERIAQLGKSALLHGIGKLVLPDRILLSPVPLQ
GDDLQLLHRHAVAGRDALLAAEAKLGSVPDFLRDARDIVYSQHENWDGSGYPQGLRGEQI
PLAARLMALVGDYEEMTSQHPYRQSVSHAEAQQRIGAASGTRFDPSVVLAFIEAEQEFAA
IAQRLADDAAAIHGELQRLDESLGESIELTLPPS