Protein Info for OH686_06285 in Pseudomonas sp. S08-1

Annotation: Two-component system sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1251 transmembrane" amino acids 14 to 35 (22 residues), see Phobius details amino acids 315 to 337 (23 residues), see Phobius details PF03924: CHASE" amino acids 83 to 267 (185 residues), 196.6 bits, see alignment E=1.7e-61 TIGR00229: PAS domain S-box protein" amino acids 353 to 479 (127 residues), 103.8 bits, see alignment E=3.4e-34 amino acids 475 to 601 (127 residues), 95.4 bits, see alignment E=1.4e-31 PF00989: PAS" amino acids 358 to 466 (109 residues), 55.4 bits, see alignment E=2.6e-18 amino acids 478 to 591 (114 residues), 53.3 bits, see alignment E=1.2e-17 PF13188: PAS_8" amino acids 358 to 408 (51 residues), 35 bits, see alignment (E = 4.5e-12) amino acids 478 to 530 (53 residues), 35.6 bits, see alignment (E = 2.7e-12) PF08448: PAS_4" amino acids 363 to 474 (112 residues), 36.9 bits, see alignment E=1.7e-12 amino acids 484 to 595 (112 residues), 32.3 bits, see alignment E=4.5e-11 PF13426: PAS_9" amino acids 367 to 472 (106 residues), 46.7 bits, see alignment E=1.5e-15 amino acids 488 to 593 (106 residues), 49.2 bits, see alignment E=2.5e-16 PF00512: HisKA" amino acids 615 to 682 (68 residues), 66.3 bits, see alignment 9.3e-22 PF02518: HATPase_c" amino acids 730 to 845 (116 residues), 106.2 bits, see alignment E=6.1e-34 PF00072: Response_reg" amino acids 871 to 975 (105 residues), 44.7 bits, see alignment E=6.3e-15 amino acids 992 to 1072 (81 residues), 45.8 bits, see alignment 2.8e-15 amino acids 1125 to 1235 (111 residues), 92.5 bits, see alignment E=9.1e-30

Best Hits

Predicted SEED Role

"FIG00959769: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1251 amino acids)

>OH686_06285 Two-component system sensor histidine kinase (Pseudomonas sp. S08-1)
MDGTAPIFHSRKPWIPLLISLVLLIGLGALVFWQWRTLEQSNRQAQEQRFALAVDGVELS
VRERMRAYEMVLRGMAGLMAGSDQVSNEEWQRAADQLQLQEQYPGIQALSWNRYLRQGEL
QSFIDTERASGRGDFQAYPSGEREAYLVVTFINPLDWRNRRALGFDMYSEATRRAAIERA
RDSGEAVLTGPLRLRQETEKDAQTGMLLYLPVFRPNAPLSTTDERREALHGMVAGTFRLA
DLMHGILGSGGSQFEIKLLDLADPAQPLLSRSGMQSHNPRFRAQRTLSIYGREWQLDVGS
TAAYEAALGDGDLPISLGTGLLAALLLSLLVGGFLFLRDRALGDSERQRQQLRESEGRFR
LVVEASPNAIVLVDGSGKVVMVNRQVELMFGYERDELLGQPVERLLPEQLRQGHPAMRQA
YQKAPEQRRMGGNRELFGQHRDGRLIPLEVGLAPIRVGEEMLVQAVIIDISERKSAEERF
RLVVEASPNAIVLVDGKGRLSMVNRQTEQMFGYERAEMLGQPVEMLLPEAARAQHPSLRD
GFIKDPSPRRMGGNRELFGQHRDGRLIPLEVGLSPIRADGERLVQAVIIDISERKAAEQR
LREQAEQLALANRYKSEFLANMSHELRTPLNSILILSEQLRHNVAGNLTEKQVKHADIVY
KAGNDLLQLINDVLDLAKIEAGRVQLKLEPLNIHDLLVELDSSLRPMAEIKGLRLLTHLE
PGVARMIHSDRGRLQQILRNLLSNALKFTEHGEVELSIGLSPVSLDDERETLQFVVRDSG
IGIDPAQHERIFQAFQQIDGSTSRRFGGTGLGLAITRQLVEVLGGQISLESTPGQGSRFI
VRLPVVALNPQAKEDESLSATPQRSGSGPAVLIVEDDPNFAAVIAEEAQAHGFSSVHCRN
GKQAIGLLQSERFVAVILDILLPDISGWQIYRRLRGLMQYRDVPVHIVSCVPQPQDWHGD
GTRYLVKPVARQDLERVFEDIVVLSAPSRDLLLVEDVEVEREHYREHLVQMGFRVTAVAS
AEQARQAYAAQSFDALVIDLDLPDQDGFDLLETLQRERALRDTQVVINTGVDITRQDLQR
LRRYSAVVVRKSGDDLRPLGAALQGFLSTVREPPADGSQLAGKRVLLVDDDIRNIYAMTA
LLDELGLAVVPAKDGEEALVAFDREPFDLVLMDMAMPNMDGYTATRILKDERGCGIPVIA
LTAHAMKGDREKCITAGCDDYLAKPVARQELLEMLHRWLAASAQSRRQARG