Protein Info for OH686_06220 in Pseudomonas sp. S08-1

Annotation: Sulfate transport system protein cysZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 transmembrane" amino acids 26 to 47 (22 residues), see Phobius details amino acids 67 to 95 (29 residues), see Phobius details amino acids 147 to 175 (29 residues), see Phobius details amino acids 211 to 238 (28 residues), see Phobius details PF07264: EI24" amino acids 11 to 227 (217 residues), 176.1 bits, see alignment E=4.8e-56

Best Hits

Swiss-Prot: 78% identical to CYSZ_PSEA8: Sulfate transporter CysZ (cysZ) from Pseudomonas aeruginosa (strain LESB58)

KEGG orthology group: K06203, CysZ protein (inferred from 79% identity to pba:PSEBR_a4718)

Predicted SEED Role

"Sulfate transporter, CysZ-type" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (249 amino acids)

>OH686_06220 Sulfate transport system protein cysZ (Pseudomonas sp. S08-1)
MLNPALSGPQYLGEGLKLVLSPGLRLFVLLPLAVNTLLFLGLIVLAMQQFGIWMDSLMPN
LPDWLSFLTYVLTPLFFLLVLVIMFFTFTLLANIIAAPFNGFLAEKVEVVLRGRDDFPPF
SWAELMAMMPRTIGREMRKLAYFLPRAIPLLILTFVPVLNLVAAPLWILFGIWMMAVQYI
DYPADNNKLGWNEMLAWLREKRWQSLGFGGTVYLALLIPFVNILVMPAAVAGATLFWVRE
RSEAVPAPQ