Protein Info for OH686_03875 in Pseudomonas sp. S08-1

Annotation: Similarity with glutathionylspermidine synthase , group 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03738: GSP_synth
  • amino acids 12 to 369 (358 residues), 479.4 bits, E=4.5e-148

Best Hits

Swiss-Prot: 46% identical to YGIC_ECO57: Putative acid--amine ligase YgiC (ygiC) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 62% identity to gpb:HDN1F_15260)

MetaCyc: 46% identical to peptide--spermidine ligase YgiC (Escherichia coli K-12 substr. MG1655)
6.3.1.-

Predicted SEED Role

"Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 1" in subsystem Glutathionylspermidine and Trypanothione (EC 6.3.1.8)

MetaCyc Pathways

• glutathionylspermidine biosynthesis (1/1 steps found)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.1.8

Protein Sequence (371 amino acids)

>OH686_03875 Similarity with glutathionylspermidine synthase , group 1 (Pseudomonas sp. S08-1)
MRRIDFTPRPHWRQQCEELGFTFHSIDGTYWDESAAYELSLAQVETLEAAAEELHRLYLD
AAQWVIEQRHFAPFALPPSAEQLIVDSWQRQEPALYGRFDFSWNGQGKPKLLEYNADTPT
GLLEASVVQWYWLRDVLPEADQFNSLHEKLIERWRQIGHGHVHFAAIEGHEEDTGNVLYM
LDVAHQAGLPTHYVPVEAIGYDEQRRIFVDQHERSIEHCFKLYPWEWLLQDEFSSHVGSS
GIRFQEPAWKLLLSSKAMLPILWQRNPGHPNLLPSSFAADLPEPYVRKPLYAREGQNIQI
VGTGQTLESDGPHAADTCIYQAYAPLPRFADSYTVLGCWMVGDQTAGLGIREDATPITRD
SSRFLPHYFIE