Protein Info for OH686_02745 in Pseudomonas sp. S08-1

Annotation: flagellar biosynthesis protein FlhA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 709 transmembrane" amino acids 22 to 42 (21 residues), see Phobius details amino acids 48 to 66 (19 residues), see Phobius details amino acids 73 to 93 (21 residues), see Phobius details amino acids 123 to 143 (21 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details amino acids 243 to 270 (28 residues), see Phobius details amino acids 288 to 307 (20 residues), see Phobius details amino acids 313 to 330 (18 residues), see Phobius details TIGR01398: flagellar biosynthesis protein FlhA" amino acids 23 to 706 (684 residues), 861.3 bits, see alignment E=2.4e-263 PF00771: FHIPEP" amino acids 33 to 698 (666 residues), 883.4 bits, see alignment E=5.3e-270

Best Hits

Swiss-Prot: 47% identical to FLHA_AQUAE: Flagellar biosynthesis protein FlhA (flhA) from Aquifex aeolicus (strain VF5)

KEGG orthology group: K02400, flagellar biosynthesis protein FlhA (inferred from 94% identity to pmk:MDS_1866)

Predicted SEED Role

"Flagellar biosynthesis protein FlhA" in subsystem Flagellar motility or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (709 amino acids)

>OH686_02745 flagellar biosynthesis protein FlhA (Pseudomonas sp. S08-1)
MAVDRAQLIGDVRSNLAGLRHGNLGIPLLLLVMLAMVMLPIPPFLLDVLFTFSIALSIVV
LLVAIYSLRPLDFAVFPTVLLAATLLRLALNVASTRVVLLHGQEGHDAAGKVIQAFGEVV
IGGNYVVGAVVFAILMIINFVVVTKGAGRISEVSARFTLDAMPGKQMAIDADLNAGLIDQ
AEAKKRRVEVAQEADFYGSMDGASKFVRGDAVAGLLILFINLIGGMAIGVLQHDLAFAEA
GRIYTLLTIGDGLVAQIPSLLLSTAAAIMVTRVSTSEDMGAQVSRQMFASPKALAVSSAI
MIAMGLVPGMPHFSFISLGLVAAGAAYWIAHKQRKTKEDAVKEVQRQQELLPAQKAQEVK
ELGWDDVTPVDMVGLEVGYRLIPLVDRNQGGQLLARIKGVRKKLSQEMGFLMPSVHIRDN
LDLLPNAYRLTLMGVSVAEAEVYPERELAINPGQVFGTLNGIAAKDPAFGLEAVWIDPTQ
RDQAQSLGYTVVDASTVVATHLNQVLHKHAHELLGHEEVQQLMQLLAKSSPKLAEELVPG
MVSLSTLLKVLQTLLQEQVPVRDIRSIAEAISNVAGKSQDPAAMVAAVRVALSRAIVQSI
VGLEPELPVITLEPRLEQLLLNSLQKAGQGSEDGILLEPGMAEKLQRSLVEAAQRQEMLG
KPVILLVAGPVRAMLSRFARLAVPAMHVLAYQEIPDNKQVTIVATVGQN