Protein Info for OH686_02470 in Pseudomonas sp. S08-1

Annotation: ABC transporter, substrate-binding protein (cluster 1, maltose/g3p/polyamine/iron)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF01547: SBP_bac_1" amino acids 42 to 305 (264 residues), 99.4 bits, see alignment E=4.1e-32 PF13416: SBP_bac_8" amino acids 66 to 342 (277 residues), 74.1 bits, see alignment E=1.7e-24

Best Hits

Swiss-Prot: 48% identical to SP39_BRUAB: Probable sugar-binding periplasmic protein (BruAb2_0537) from Brucella abortus biovar 1 (strain 9-941)

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 85% identity to pmy:Pmen_1150)

Predicted SEED Role

"Glucose ABC transport system, periplasmic sugar-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (417 amino acids)

>OH686_02470 ABC transporter, substrate-binding protein (cluster 1, maltose/g3p/polyamine/iron) (Pseudomonas sp. S08-1)
MNAISRLAVVVSLASLFPLSALAGEVEVLHWWTSGGEKRAADTLQKLVEDKGHTWKDFAV
AGGGGEAAMTVLKTRAVSGNPPSAAQIKGPDIQEWGELGLLTELDEVASEGKWDSLLPKQ
VASVMKYDDHYVAVPVNVHRVNWLWINPEVFKKAGATPPTTLDEFFAAADKLKAAGFIPL
AHGGQPWQDGTVFEDLVFAILGPQGYHKAFVEQDKATLTGDKMVEVFATLKKLRGYIDAD
AAGRDWNTAAGLVINGKAGMQIMGDWAKSEWTAAGKVAGQDYQCLPFPGTQGSFAYNIDS
LAMFKLSDEDNRKAQNDLARTVMSPEFQQFFNQNKGSIPVRLDQDMSSFDSCAQQSMKDF
KEAAAGDGLQPSLAHGMAASSYVQGAVFDVVTNFFNDPAADPKKAAQQLAAAIEAVQ