Protein Info for OH686_01420 in Pseudomonas sp. S08-1

Annotation: Oxidoreductase, short-chain dehydrogenase/reductase family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 PF00106: adh_short" amino acids 42 to 232 (191 residues), 182.7 bits, see alignment E=8.8e-58 PF08659: KR" amino acids 45 to 218 (174 residues), 49.4 bits, see alignment E=8.1e-17 PF13561: adh_short_C2" amino acids 48 to 280 (233 residues), 222.3 bits, see alignment E=1.1e-69

Best Hits

Swiss-Prot: 61% identical to YHDF_BACSU: Uncharacterized oxidoreductase YhdF (yhdF) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 74% identity to avn:Avin_11090)

MetaCyc: 45% identical to NADP+-dependent aldehyde reductase (Escherichia coli K-12 substr. MG1655)
1.1.1.-

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>OH686_01420 Oxidoreductase, short-chain dehydrogenase/reductase family (Pseudomonas sp. S08-1)
MSEKQTLPPQHQDIPHGSEAQMDPPPVYIDERYRGAGKLEGKVAVISGADSGIGRAVAVH
FAEEGCDIVLLYFDRDEDAKHTQAEIERRGRQVLPLAGDVADAGFCSQVVEQAIGKWGHI
DILVNNAGEQQPQEGLEDISEEQWEQTFRTNIFGMFQLTKAALPHLKDGSAIINTTSITA
YKGNPMLLDYSSTKGAITTFTRSLALNLAKRGIRVNAVAPGPIWTPLIASTFPPEKVATF
GSDTPMQRPGQPAEVAPAFVYLASNDSSYVSGQVLHVNGGSVVNG