Protein Info for NOLOHH_17375 in Escherichia coli ECOR27
Name: ynjE
Annotation: thiosulfate sulfurtransferase YnjE
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 99% identical to YNJE_ECOLI: Thiosulfate sulfurtransferase YnjE (ynjE) from Escherichia coli (strain K12)
KEGG orthology group: K01011, thiosulfate/3-mercaptopyruvate sulfurtransferase [EC: 2.8.1.1 2.8.1.2] (inferred from 100% identity to eoh:ECO103_1950)MetaCyc: 99% identical to molybdopterin synthase sulfurtransferase (Escherichia coli K-12 substr. MG1655)
RXN-12473 [EC: 2.8.1.11]
Predicted SEED Role
"Putative thiosulfate sulfurtransferase ynjE (EC 2.8.1.1)" (EC 2.8.1.1)
MetaCyc Pathways
- molybdopterin biosynthesis (6/6 steps found)
- L-cysteine degradation III (2/2 steps found)
- thiosulfate disproportionation IV (rhodanese) (1/1 steps found)
- sulfide oxidation IV (mitochondria) (2/5 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.8.1.1, 2.8.1.2
Use Curated BLAST to search for 2.8.1.1 or 2.8.1.11 or 2.8.1.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (435 amino acids)
>NOLOHH_17375 thiosulfate sulfurtransferase YnjE (Escherichia coli ECOR27) MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAIDTRPSAFYNGWPQTLNG PSGHEPAALNLSASWLDKMSTEQLYEWIKQHNLKTDAPVALYGNDKDVDAVKTRLQKAGF THISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEVTAKPAGDWKVIEAAWGAPKL YLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKHGIRHDTTVILYGRDVYAGARVA QIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKVKAEPDFGVKIPAQPQLMLDMEQAR GLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGEIAGARWGHAGSDSTHMEDFHNPDGTM RSADDITAMWKAWNIKPEQQVSFYCGTGWRASETFMYARAMGWKNVSVYDGGWYEWSSDP KNPVATGERGPDSSK