Protein Info for NOLOHH_15775 in Escherichia coli ECOR27

Name: wzx
Annotation: O104 family O-antigen flippase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 64 (23 residues), see Phobius details amino acids 85 to 106 (22 residues), see Phobius details amino acids 112 to 134 (23 residues), see Phobius details amino acids 153 to 172 (20 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details amino acids 230 to 248 (19 residues), see Phobius details amino acids 254 to 278 (25 residues), see Phobius details amino acids 298 to 319 (22 residues), see Phobius details amino acids 332 to 359 (28 residues), see Phobius details amino acids 370 to 389 (20 residues), see Phobius details amino acids 395 to 413 (19 residues), see Phobius details PF01554: MatE" amino acids 236 to 358 (123 residues), 28.6 bits, see alignment E=1.1e-10 PF14667: Polysacc_synt_C" amino acids 337 to 421 (85 residues), 46.2 bits, see alignment E=5.4e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to eck:EC55989_2290)

MetaCyc: 100% identical to Escherichia coli O:104 antigen repeat unit flippase (Escherichia coli O104)
7.5.99.a [EC: 7.5.99.a]

Predicted SEED Role

"FIG00641555: hypothetical protein"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.99.a

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>NOLOHH_15775 O104 family O-antigen flippase (Escherichia coli ECOR27)
MNMLKYIQPILSLLLRMFTVISSFLFSWIVARLFGAESAGTIFFYITIITIFVTIASQGA
ELGIAKAVARLAGNEKKQIGVLRSVVLRTNKMFLILSPAFLFYLLYEGYEINNLIILFVL
MLILGYCFLYMNILSFFYQGIGNITMMILSQRAIFNLFSFLLIAFLWGVFYLENKKLSFM
TLEQQFVIITIAGLISFGLLYLYHRLTSNYSPLYYKPEGFDKSCKELFKIQLLQIITMYG
SQIIINIFSVKADIAGFIVAQRISTLLGFFVLAISGVISSQVSRAYSLKDFTSIHKSAYH
SVLFSSFLGVPVAGILILYSKECLLLFGNDFYQYQAVLIVLIVSQVFNCLTGACDIILMF
IDGEKEHKKNVLTGTFLAIVLSFILIPIYSALGAAIATAFSAIIVNILDVISIKKKAGFW
IFKTV