Protein Info for NOLOHH_15255 in Escherichia coli ECOR27

Name: yehP
Annotation: Uncharacterized protein YehP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 PF05762: VWA_CoxE" amino acids 151 to 372 (222 residues), 232.5 bits, see alignment E=4.2e-73 PF13519: VWA_2" amino acids 217 to 308 (92 residues), 33.6 bits, see alignment E=5.2e-12

Best Hits

Swiss-Prot: 99% identical to YEHP_ECOLI: Uncharacterized protein YehP (yehP) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ecw:EcE24377A_2409)

Predicted SEED Role

"Mg-chelatase subunit ChlD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>NOLOHH_15255 Uncharacterized protein YehP (Escherichia coli ECOR27)
MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEWLYGRDPERLQRGERSG
GLGGSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVVTNLDVLERMQPSESLLRA
VLHTKHLMNPEVLAAARQIVRQVVEEIMARLAKEVRQAFSGVRDRRRRSFIPLARNFDFK
STLRANLQHWHPQHGKLYIESPRFNSRIKRQSEQWQLVLLVDQSGSMVDSVIHSAVMAAC
LWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQLGGGTNIASAVEYGRQLIEQPAKS
VIILVSDFYEGGSSSLLTHQVKKCVQSCIKVLGLAALDSTATPCYDHDTAQALVNVGAQI
AAMTPGELASWLAENLQS