Protein Info for NOLOHH_12590 in Escherichia coli ECOR27

Name: yqaB
Annotation: fructose-1-phosphate/6-phosphogluconate phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 188 TIGR02009: beta-phosphoglucomutase family hydrolase" amino acids 5 to 185 (181 residues), 222.2 bits, see alignment E=9.3e-70 PF00702: Hydrolase" amino acids 7 to 179 (173 residues), 105.9 bits, see alignment E=7.3e-34 PF13419: HAD_2" amino acids 8 to 183 (176 residues), 103.8 bits, see alignment E=2.4e-33 PF12710: HAD" amino acids 9 to 138 (130 residues), 28.4 bits, see alignment E=4.5e-10 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 121 to 183 (63 residues), 57.4 bits, see alignment E=2.8e-19 PF13242: Hydrolase_like" amino acids 141 to 185 (45 residues), 26 bits, see alignment E=1.4e-09

Best Hits

Swiss-Prot: 98% identical to YQAB_ECOLI: Fructose-1-phosphate phosphatase YqaB (yqaB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to eco:b2690)

MetaCyc: 98% identical to fructose-1-phosphate phosphatase YqaB (Escherichia coli K-12 substr. MG1655)
3.1.3.-

Predicted SEED Role

"Putative phosphatase YqaB" in subsystem 2-phosphoglycolate salvage

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (188 amino acids)

>NOLOHH_12590 fructose-1-phosphate/6-phosphogluconate phosphatase (Escherichia coli ECOR27)
MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMIALNGSPTWRIAQAIIE
LNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGRRPMAVGTGSESAIAEALL
AHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPTQCVVFEDADFGIQAARAAGM
DAVDVRLL