Protein Info for NOLOHH_11750 in Escherichia coli ECOR27

Name: ygeH
Annotation: HilA family transcriptional regulator YgeH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 458 PF00486: Trans_reg_C" amino acids 28 to 101 (74 residues), 46.2 bits, see alignment E=2e-16

Best Hits

Swiss-Prot: 100% identical to YGEH_ECOLI: Uncharacterized protein YgeH (ygeH) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b2852)

Predicted SEED Role

"Putative invasion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (458 amino acids)

>NOLOHH_11750 HilA family transcriptional regulator YgeH (Escherichia coli ECOR27)
MDLENKFSYHFLEGLTLTEDGILTQGNEQVYIPQKELGVLIVLLESAGHVVLKDMIIESV
WKNIIVSDESLTRCIYSLRCIFEKIGYDRCIETIYRKGYRFSGQVFKTKINEDNTSDYSI
AIFPFTTSLNTLDPLILNQELVQIISNKKIDGLYTYPMAATNFCNDHISQNSFLSRFKPD
YFVTGRINQNNAVNTLYIELIDAKNLFLIASNHLPVDELHNTSQFIIDNILQTVHKPERS
VRLAKQDQGYKNHYLSDEMLAGKKELYDFTPESIYRAMTIFDRLQNKSDIQTLKTECYCL
LAECHMSLALHGKSELELAAQKALELLDYVSDITTVDGKILAIMGLITGLSGQAKVSHIL
FEQAKIHSTDIASLYYYRALVHFHNEKIEEARICIDKSLQLEPRRRKAVVIKECVDMYVP
NPLKNNIKLYYKETESESHRVIIDNILKLKQLTRICMR