Protein Info for NOLOHH_11160 in Escherichia coli ECOR27

Name: sprT
Annotation: SprT family zinc-dependent metalloprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 151 PF10263: SprT-like" amino acids 5 to 101 (97 residues), 81 bits, see alignment E=5.8e-27 PF17283: Zn_ribbon_SprT" amino acids 112 to 150 (39 residues), 34.4 bits, see alignment E=1.9e-12

Best Hits

Swiss-Prot: 100% identical to SPRT_ECO8A: Protein SprT (sprT) from Escherichia coli O8 (strain IAI1)

KEGG orthology group: K02742, SprT protein (inferred from 99% identity to eco:b2944)

Predicted SEED Role

"Protein sprT"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (151 amino acids)

>NOLOHH_11160 SprT family zinc-dependent metalloprotease (Escherichia coli ECOR27)
MRRLREKLTQANLKLGRNYPEPKLSYTQRGTSAGTAWLESYEIRLNPVLLLENSEAFIEE
VVPHELAHLLVWKHFGRVAPHGKEWKWMMESVLGVPARRTHQFELQSVRRNTFPYRCKCQ
EHQLTVRRHNRVVRGEAVYRCVHCGEQLVAK