Protein Info for NOLOHH_08820 in Escherichia coli ECOR27

Name: greB
Annotation: transcription elongation factor GreB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 158 TIGR01461: transcription elongation factor GreB" amino acids 2 to 157 (156 residues), 292.9 bits, see alignment E=2.4e-92 PF03449: GreA_GreB_N" amino acids 6 to 74 (69 residues), 92.5 bits, see alignment E=1.5e-30 PF01272: GreA_GreB" amino acids 81 to 155 (75 residues), 82.7 bits, see alignment E=1.4e-27

Best Hits

Swiss-Prot: 100% identical to GREB_ECOL6: Transcription elongation factor GreB (greB) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K04760, transcription elongation factor GreB (inferred from 99% identity to ecd:ECDH10B_3581)

Predicted SEED Role

"Transcription elongation factor GreB" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (158 amino acids)

>NOLOHH_08820 transcription elongation factor GreB (Escherichia coli ECOR27)
MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSENADYQYNKKRLREIDR
RVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGVTHRFRIVGYDEIFGRKDYISI
DSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP