Protein Info for NOLOHH_07000 in Escherichia coli ECOR27

Name: fimD
Annotation: fimbrial protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 840 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF13954: PapC_N" amino acids 29 to 174 (146 residues), 137.7 bits, see alignment E=4.2e-44 PF00577: Usher" amino acids 192 to 749 (558 residues), 617.9 bits, see alignment E=3.1e-189 PF13953: PapC_C" amino acids 758 to 824 (67 residues), 61.7 bits, see alignment E=7e-21

Best Hits

KEGG orthology group: K07347, outer membrane usher protein (inferred from 100% identity to ecr:ECIAI1_3910)

Predicted SEED Role

"type 1 fimbriae anchoring protein FimD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (840 amino acids)

>NOLOHH_07000 fimbrial protein (Escherichia coli ECOR27)
MMTTRIVVGLTAGTCLIFSQNLMAEVSVFNPALLEIDHQSGVDIRQFNRANLMPPGVYSV
DIFINGKMFERQDVTFVQDNPDADLHACFIAIKKTLSSFGIKVDALKSFNDVDETVCLDP
APRIEGSSWQFDSDKLQLNISIPQIYMDAMAYDYISPTRWDEGINALTINYDFSGSHTLR
SDYGSQETDTSYLNLRNGLNIGPWRLRNYSTLNTSDGRAEYNSISTWIQRDIAALRSQIM
IGDTWTASDIFDSTQIRGARLYTDNDMLPASQNGFAPVVRGIAKSNATVIIRQNGYVIYQ
SAVPQGAFEITDLNTASTGGDLDVTIKEEDGSEQRFTQPYASLAILKREGQTDVDVSVGE
LRDEDGFTPDVLQAQILHGFSHGITLYGGMQAAENYGSAALGVGKDLGALGAISFDVTHA
RANFSHDDTETGQSYRFLYSKRFDDTDTSLRLVGYRYSTEGYYTLNEWASRRNSPEDFWE
TGNRRSRVEGTLTQSLGRDYGNLYLTLSRQQYWHTDDVERLMQFGYSSSWKRLSWNVSWS
YSNTARQGTGNNHASDNTSEQIYMLSLSVPLSGWWGNSYATYSVSQNDNSGSSHQLGLSG
TALERNNLSWNLMQSYNSHDDEVGGNMSLTYDGSYGTVNGSYNYSQNSQRLNYGIRGGIL
AHSEGVTLSQELGETIALVKAPGAAGLEIDNMRGAATDWRGYTVKTQLNPYDENRVAISD
NYFSKSNIELDNTVVTMVPTRGAVVKAEFVTHVGYRVLFRVLNANGKPVPFGAIAAIQDA
SLADSGIVGDRGELYLSGLPEKGQVTLSWGENASTKCIFNYSLSTPESESGLIEQGVTCH