Protein Info for NOLOHH_06030 in Escherichia coli ECOR27
Name: rhaA
Annotation: L-rhamnose isomerase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to RHAA_ECO55: L-rhamnose isomerase (rhaA) from Escherichia coli (strain 55989 / EAEC)
KEGG orthology group: K01813, L-rhamnose isomerase [EC: 5.3.1.14] (inferred from 99% identity to eco:b3903)MetaCyc: 99% identical to L-rhamnose isomerase (Escherichia coli K-12 substr. MG1655)
L-rhamnose isomerase. [EC: 5.3.1.14]; 5.1.3.- [EC: 5.3.1.14]
Predicted SEED Role
"L-rhamnose isomerase (EC 5.3.1.14)" in subsystem L-rhamnose utilization (EC 5.3.1.14)
MetaCyc Pathways
- superpathway of fucose and rhamnose degradation (12/12 steps found)
- L-rhamnose degradation I (5/5 steps found)
- L-lyxose degradation (4/4 steps found)
- superpathway of pentose and pentitol degradation (16/42 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 5.3.1.14
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (419 amino acids)
>NOLOHH_06030 L-rhamnose isomerase (Escherichia coli ECOR27) MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQ ATGNYPGKARNASELRTDLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVE WAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPS VMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVG SNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVL LDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAEL RKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPTGSEWLESVRAYEKAILSQRG