Protein Info for NOLOHH_05390 in Escherichia coli ECOR27

Annotation: ShET2 enterotoxin, N-terminal region

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 524 PF07906: Toxin_15" amino acids 121 to 379 (259 residues), 325.5 bits, see alignment E=1.7e-101

Best Hits

KEGG orthology group: K06867, (no description) (inferred from 99% identity to eoi:ECO111_4829)

Predicted SEED Role

"Ankyrin-repeat protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (524 amino acids)

>NOLOHH_05390 ShET2 enterotoxin, N-terminal region (Escherichia coli ECOR27)
MITRIPRSSFSANINNTAQTNEHQTLSELFYKELEDKFSGKELATPLLKSFSENCRQNGR
HIFSNKDFVIKFSTSVLQADKKEITIINKNENTTLTQTIAPIFEEYLMEILPQRSDTLDK
QELNLKSDRKEKEFPRIKLNGQCYFPGRPQNRIVCRHIAAQYINDIYQNVDYKPHQDDYS
SAEKFLTHFNKKCKNQTLALVSSRPEGRCVAACGDFGLVMKAYFDKMESNGISVMAAILL
VDNHALTVRLRIKNTTEGCTHYVVSVYDPNVTNDKIRIMSESKEDIKHYSLMDFMNVDYS
LLKWSNDHVINQSVAIIPALPKEQLLMLKGSVDEITPPLSPATMNLLMAIGQNHQLTQLM
IQLQKMPELHRTEMLTAYNSGHMNVINTIFNALPTLFNTFKFDKKNMKPLLLANNSNEYP
GLFSAIQHKQQNVVETVYLALSDHARLFGFTAEDIMDFWQHKAPQKYSAFELAFEFGHRV
IAELILNTLNKMAESFGFTDNPRYIAEKNYMEALLKKASPHTVR