Protein Info for NOLOHH_02085 in Escherichia coli ECOR27

Name: rtcB
Annotation: RNA ligase RtcB family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 379 TIGR03073: release factor H-coupled RctB family protein" amino acids 12 to 367 (356 residues), 617.3 bits, see alignment E=3.9e-190 PF01139: RtcB" amino acids 29 to 95 (67 residues), 47 bits, see alignment E=1.1e-16 amino acids 100 to 372 (273 residues), 203.6 bits, see alignment E=3.3e-64

Best Hits

KEGG orthology group: None (inferred from 100% identity to eoh:ECO103_0250)

Predicted SEED Role

"Protein with similarity to RtcB" in subsystem RNA 3'-terminal phosphate cyclase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (379 amino acids)

>NOLOHH_02085 RNA ligase RtcB family protein (Escherichia coli ECOR27)
MGNYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVGMPDLHPGRGYPIGAAF
FSVGRFYPALVGNDIGCGMALWQTDILTRKYNADKFEKRLSDLDDVAEESWLEENLPSAF
AQHPWRSSLGSIGGGNHFAELQQVDQIINAELFALAGLDAQHLQLLVHSGSRGVGQSILQ
RHIASFSHHGLPQGSDDALRYIAEHDDALAFACINRQMIALRIMQQVKATGSPVLDVAHN
FVSACQIGDQQGWLHRKGATPDDNGLVIIPGSRGDYSWIVQPVANEKTLHSLAHGAGRKW
GRTECKGRLAAKYTATQLSRTELGSRVICRDKQLIFEEAPQAYKSAESVVQCLVQAGLII
PVARLRPVLTLKNSGGKKG