Protein Info for NIAGMN_25625 in Escherichia coli ECRC102

Name: vgrG
Annotation: Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 TIGR03361: type VI secretion system Vgr family protein" amino acids 4 to 312 (309 residues), 420.8 bits, see alignment E=7.5e-130 TIGR01646: Rhs element Vgr protein" amino acids 6 to 295 (290 residues), 300.9 bits, see alignment E=2e-93 PF05954: Phage_GPD" amino acids 6 to 122 (117 residues), 79.3 bits, see alignment E=3e-26 PF04717: Phage_base_V" amino acids 179 to 245 (67 residues), 55 bits, see alignment E=8.6e-19

Best Hits

Predicted SEED Role

"VgrG-3 protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (497 amino acids)

>NIAGMN_25625 Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly (Escherichia coli ECRC102)
VSTLCISQFRYSAQIRPSSVVTKDYTFKRPGWAGRFDQEGQYQDYQRTQYEVYDYPGRFK
GAHGQNFARWQMDGWRNNAEVARGTSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHG
EQPQAVPGRRGSGTTLNNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEH
GRVRVKFNWDRYNPSNQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPII
MGRTYHQENRTPGSLPGTKTQMTIRSKNYKGSGFNELKFDDATGKEQVYIHAQKNMNTEV
LNNRTTDVINNHAETIGNNQMIAVTNNQIQTVGVNQIETVGSNQIINVGSVQVETIGLVR
ALTVGVAYQTTVGGIMNTSVALMQSSQIGLHKSLRVGLGYDVKVGNNVTFTVGKTKKDDT
GQTAIYSAGEHLELCCGKARLVLTKDGQIFLNGTKIHLQGKEQVNGDSLLINWNCAASKS
PPKTPDEKQDTPDMREY