Protein Info for NIAGMN_25620 in Escherichia coli ECRC102

Name: rhsA
Annotation: RHS element protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 PF20148: DUF6531" amino acids 46 to 123 (78 residues), 65.4 bits, see alignment 7.1e-22 PF05593: RHS_repeat" amino acids 368 to 399 (32 residues), 24.7 bits, see alignment (E = 3.9e-09) amino acids 416 to 447 (32 residues), 28.9 bits, see alignment (E = 1.8e-10) amino acids 457 to 489 (33 residues), 24 bits, see alignment (E = 6.2e-09) amino acids 541 to 575 (35 residues), 33.5 bits, see alignment (E = 6.4e-12) amino acids 582 to 618 (37 residues), 43.2 bits, see alignment (E = 6.1e-15) amino acids 624 to 659 (36 residues), 23.4 bits, see alignment (E = 9.4e-09) amino acids 644 to 681 (38 residues), 31.7 bits, see alignment (E = 2.3e-11) TIGR01643: YD repeat (two copies)" amino acids 416 to 451 (36 residues), 24.4 bits, see alignment (E = 3.1e-09) amino acids 458 to 490 (33 residues), 16.6 bits, see alignment (E = 8.7e-07) amino acids 543 to 578 (36 residues), 22.3 bits, see alignment (E = 1.4e-08) amino acids 582 to 622 (41 residues), 43.2 bits, see alignment (E = 3.6e-15) amino acids 603 to 634 (32 residues), 24.7 bits, see alignment (E = 2.4e-09) amino acids 644 to 685 (42 residues), 28.4 bits, see alignment (E = 1.7e-10) PF03527: RHS" amino acids 1152 to 1188 (37 residues), 59.8 bits, see alignment (E = 2.6e-20) TIGR03696: RHS repeat-associated core domain" amino acids 1179 to 1256 (78 residues), 79.2 bits, see alignment 2.5e-26

Best Hits

Swiss-Prot: 93% identical to RHSD_ECOLI: Protein RhsD (rhsD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to ecw:EcE24377A_1639)

Predicted SEED Role

"core protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1400 amino acids)

>NIAGMN_25620 RHS element protein (Escherichia coli ECRC102)
MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMTSGNPVNPLLGAKVLPG
ETDLALPGPLPFILSRTYSSYRTRTPAPVGIFGPGWKAPSDIRLQLRDDALVLNDNGGRS
IHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLARLWGALPPDIRLSPHLYLATNSAQ
GPWWILGWSERVPGAEDVLPAPLPPYRVLTGMADRFGRTLTYRREAAGDLAGEITGVTDG
AGREFRLVLTTQAQRAEEARKQHTASLSSPDTPRPLSDSAFPDTLPGTEYGPDRGIRLSA
VWLTHDPAYPESLPGAPLARYTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAG
RPEMRYRYDDTGRVVEQLNPAGLSYRYQYEQDRITVTDSLNRREVLHTEGGAGLKRVVKK
ELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDITTPDGRETKFYYNDGNQ
LTAVVSPDGLESRRAYDEPGRLVSETSRCGDVIRYAYDNPHSELPATTTDATGSTRQMTW
SRYGQLLAFTDCSGYQTRYEYDRFGQMTAVHREEGISRYRRYDNRGRLTSVKDAQGHETR
YEYNAAGDLTAVITPDGNRSETQYDAWGKAVSTTQGGLTRSMEYDLAGRITTLTNENGSR
SEFTYDALDRLVQQRGFDGRTQRYHYDLTGKLTQSEDEGLVTLWHYDESDRLTHRTVNGE
PAEQWQYDEHGWLTEISHLSEGHQVAVHYGYDDKGRLAGERQTVHNPETGELLWQHETEH
AYNEQGLANRVTPDSLPRVEWLTYGSGYLAGMKLGGTPLVEFTRDRLHRETVRSFGNNAY
ELTSTYTPAGHLQSQRLNSQVYDRDYDWNDNGDLVRISGPRQTWEYGYSATGRLESVRTL
ASDLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRHDEYGRLTEKTDR
IPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERD
LTGWMSLSRKPEVTWYGWDGDRLTTVQTDTTRIQTVYEPGSFTPLIRVETENGEREKAQR
RSLAETLQQEGSENGHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLAR
QVEPEYTPARKVHFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNEENPYYLHQPYRL
PGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPLNPIIRMDPLGLYNLY
QLLYDVWHDDSYGTSSIDITGSGDLISLGGHAGLGVAFAKKKGEMLSDICIYATACGHAG
IGGGINAAITYSETKSLPTSGVSNSVGVTVGGGVGGHFAYTYVVDVDNPESSTESVGIGA
GVDASVMTLACRTWQECWVN