Protein Info for NIAGMN_25525 in Escherichia coli ECRC102

Name: ompC2
Annotation: Outer membrane porin C 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00267: Porin_1" amino acids 27 to 366 (340 residues), 448.8 bits, see alignment E=7.7e-139

Best Hits

Swiss-Prot: 67% identical to NMPC_ECOLI: Putative outer membrane porin protein NmpC (nmpC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eok:G2583_1835)

MetaCyc: 59% identical to outer membrane porin N (Escherichia coli K-12 substr. MG1655)
RXN0-2481

Predicted SEED Role

"Outer membrane porin protein NmpC precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (366 amino acids)

>NIAGMN_25525 Outer membrane porin C 2 (Escherichia coli ECRC102)
MKLKIVAVVVTGLLAANVAHAAEVYNKDGNKLDLYGKVTALRYFTDDKRDDGDKTYARLG
FKGETQINDQMIGFGHWEYDFKGYNDEANGSRDNKTRLAYAGLKISEFGSLDYGRNYGVG
YDIGSWTDMLPEFGGDTWSQKDVFMTYRTTGVATYRNYDFFGLIEGLNFAAQYQGKNERT
DNSHLYGADYTRANGDGFGISSTYVYDGFGIGAVYTKSDRTNAQERAAANPLNASGKNAE
LWATGIKYDANNIYFAANYAETLNMTTYGDGYISNKAQSFEVVAQYQFDFGLRPSLAYLK
SKGIDLGRYGDQDMIEYIDVGATYFFNKNMSTYVDYKINLIDESDFTRAVDIRTDNIVAT
GITYQF