Protein Info for NIAGMN_25330 in Escherichia coli ECRC102

Annotation: ECSE_1600 family autotransporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1343 transmembrane" amino acids 46 to 62 (17 residues), see Phobius details PF13018: ESPR" amino acids 1 to 48 (48 residues), 52.7 bits, see alignment (E = 2.2e-18) TIGR04393: T5SS/PEP-CTERM-associated repeat" amino acids 164 to 209 (46 residues), 37.6 bits, see alignment (E = 1.7e-13) amino acids 267 to 313 (47 residues), 26.5 bits, see alignment (E = 5e-10) amino acids 318 to 369 (52 residues), 24.7 bits, see alignment (E = 1.9e-09) amino acids 375 to 417 (43 residues), 25.3 bits, see alignment (E = 1.2e-09) amino acids 580 to 624 (45 residues), 36.1 bits, see alignment (E = 4.9e-13) TIGR02601: autotransporter-associated beta strand repeat" amino acids 704 to 728 (25 residues), 20.3 bits, see alignment (E = 3.8e-08) amino acids 1253 to 1283 (31 residues), 26.7 bits, see alignment (E = 3.6e-10)

Best Hits

Swiss-Prot: 97% identical to YDEK_ECOLI: Uncharacterized lipoprotein YdeK (ydeK) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to etw:ECSP_1995)

Predicted SEED Role

"FIG00637907: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1343 amino acids)

>NIAGMN_25330 ECSE_1600 family autotransporter (Escherichia coli ECRC102)
MNRIYRVIWNCTLQVFQACSELTRRVGKTSTVNLRKSSGLTTKFSRLTLGVLLALSGSVS
GASLEVDNGQITNIDTDVAYDAYLVGWYGTGVLNILAGGNASLTTITTSVIGGNEDSEGT
VNVLGGTWRLYDSGNNARPLNVGQSGTGTLNIKQKGHVDGGYLRLGTQAAGVGTVNVEGE
DSVLTTELFEIGSYGTGSLNITDKGYVTSSIVAILGYQANSNGKVVVEKGGEWLIKNNDS
SIEFQIGNQGTGEATIREGGLITAENTIIGGNATGVGTLNVQDQDSVITVRRLYNGYFGN
GAVNISNNGLINNKEYSLVGVQDGSHGVVNVTDKGHWNFLGTGEAFRYIYIGDAGDGELN
VSREGKVDSGIITAGMKETGTGNLTVKDKNSVITNLGTNLGYDGHGEMNISNEGLVVSNG
GSSLGYGETGVGKVSITTGGIWEVNKNVYTTIGVAGVGNLNISDGGKFVSQNITFLGDKA
SGIGTLNLMDATSSFDTVGINVGNFGSGIVNVSNGATLNSTGYGFIGGNASGKGIVNIST
DSLWNLKTSSTNAQLLQVGVLGTGELNITTGGIVKARDTQIALNDKSKGDVRVDGQNSLL
ETFNMYVGTSGTGTLTLTNSGTLNVEGGEVYLGVFEPAVGTLNIGAAHGEAAADAGFITN
ATKVEFGSGEGVFVFNHTNNSDAGYQVDMLITGDDKDGKVIHDAGHTVFNAGNTYSGKTL
VNDGLLTIASHTADGVTGMGSSEVTIASPGTLDILASTNSAGDYTLTNALKGDGLMRVQL
SSSDKMFGFTHATGTEFAGVAQLKDSTFTLERDNTAALTHAMLQSDIENTTSVNVGEQSI
GGLAMNGGTLIFDTDIPAATLAEGYISVDTLVVGASDYTWKGRNYQVNGTGDVLIGVPKP
WNDPMANNPLTTLNLLEHDDNHVGVQLVKAQTVIGSGGSLTLRDLQGDEVEADKTLHIAQ
NGTVVAEGDYGFRLTTAPGDGLYVNYGLKALNIHGGQKLTLAEHGGAYGATADMSAKIGG
EGDLAINTVRQVSLSNGQNDYQGATYVQMGTLRTDADGALGNTRELNISNAAIVDLNGST
QTVETFTGQMGSTVLFKEGSLTVNKGGISQGELTGGGNLNVTGGTLAVEGLNARYNALTS
VSPNAEVSLDNTQGLGRGNIANDGLLTLKNVTGELRNSISGKGIVSATARTDVELDGDNS
RFVGQFNIDTGSALSVNEQKNLGDASVINNGLLTISTERSWAMTHSISGSGDLTKLGTGI
LTLNNDSSAYQGTTDIVGGEIAFGSDSAINTASQHINIHNSGVMSGNVTTAGDVNVMSGG
TLRVAKTTIGESAATWRMAARFK